Steady flow generation in microcirculatory systems.
نویسندگان
چکیده
In this paper we explore the mechanical generation of steady-non pulsatile-flow in microfluidic systems. The rationale of the paper is inspired in the example of cardiovascular systems where at the microscale (i.e. capillaries) the flow is steady rather than pulsatile to optimize performance. We present a solution to the generation of steady flow in engineered microfluidic systems either in open or closed loop configurations via the use of disc pumps. The disc pump consists of a flat rotating disc and utilizes both viscous drag and centrifugal force to achieve pumping. Experiments using single loop and double loop microfluidic systems are presented to characterize the disc pump. Continuous flow generated by the disc pumps can be used to separate particles based on size using recirculating loops and for extraction of small particles without disturbing the concentration of bigger particles. The potential impact of this technology includes sample separation and extraction techniques into portable microfluidic labs-on-a-chip, and long term culture systems for cells in suspension.
منابع مشابه
Heat generation and radiation effects on steady MHD free convection flow of micropolar fluid past a moving surface
This paper was concerned with studying the magnetohydrodynamic steady laminar free convection flow of a micropolar fluid past a continuously moving surface in the presence of heat generation and thermal radiation. Similarity transformation was employed to transform the governing partial differential equations into ordinary ones, which were then solved numerically using the finite element method...
متن کاملNumerical investigation of clocking in a two-stage gas turbine
Flow in the first two-stage of V 94.2 gas turbine is simulated numerically. In this turbine, the second stator is clocked relative to the first stator to different positions. Steady-state analysis was carried out by varying the circumferential relative position of the consecutive stator vanes to study the effects of the clocking on turbine performance. A density based compressible inviscid ...
متن کاملEffects of heat generation and thermal radiation on steady MHD flow near a stagnation point on a linear stretching sheet in porous medium and presence of variable thermal conductivity and mass transfer
The present paper was aimed to study the effects of variable thermal conductivity and heat generation on the flow of a viscous incompressible electrically conducting fluid in the presence of a uniform transverse magnetic field, thermal radiation, porous medium, mass transfer, and variable free stream near a stagnation point on a non-conducting stretching sheet. Equations of continuity, momentum...
متن کاملSlip Velocity in Flow and Heat Transfer of Non-newtonian Fluids in Microchannels
The steady-state fully-developed laminar flow of non-Newtonian power-law fluids is examined in a circular microchannel with slip boundary condition and under an imposed constant wall heat flux. Effects of slip as well as the hydrodynamic and thermal key parameters on heat transfer and entropy generation are investigated. The results reveal that increasing the Brinkman number and the flow behavi...
متن کاملBoundary layer Viscous Flow of Nanofluids and Heat Transfer Over a Nonlinearly Isothermal Stretching Sheet in the Presence of Heat Generation/Absorption and Slip Boundary Conditions
The steady two-dimensional flow of a viscous nanofluid of magnetohydrodynamic (MHD) flow and heattransfer characteristics for the boundary layer flow over a nonlinear stretching sheet is considered. Theflow is caused by a nonlinear stretching sheet with effects of velocity, temperature and concentrationslips. Problem formulation is developed in the pre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Lab on a chip
دوره 6 4 شماره
صفحات -
تاریخ انتشار 2006